VM Study: Medications

Prescribed pharmaceutical treatments

Medications Overview

The survey posed questions about the reported effects of the various medications often used in cases of vestibular migraine. The results show a large variation in the reported benefits of the substances, and this doesn't always reflect their rates of use within the VM sample

Sample title
No effect as likely as negative effect

An average of 32% of respondents reported 'no effect' across the medications list, of those who's tried them. A similar proportion marked 'negative effect'

Sample title
Amitryptiline the better-looking cousin

Nortriptyline has lower rates of people reporting some or strong positive effects when compared to Amitryptiline (38% v 43%), and also higher reported negative effects (49% v 38%)

Sample title
Anticonvulsant confusion

While benzo anti-convulsants were well-reported, other variations showed very low rates of success among the sample group

Sample title
Serotonin significance

In the list of medications rated most likely to have a 'strong positive effect', Serotonin antagonists, SNRIs and SSRIs rank 2,3 & 4 respectively.

Reported efficacy

Benzos most effective

Benzo anti-convulsants came in fourth in terms of adoption within the respondent group, but more than 2/3 reported either some or a strong positive effect, the highest proportion of any of the medications surveyed.

'Other anti-convulsant' was the medication option most likely to have a reported negative effect with 64% of users responding so- four times the proportion reporting negative effects from benzos.

Sample title

Antihistamines effective with low negative reports

MalaDIO has devised the Calculated Efficacy Value which takes the positive reported effects and subtracts reports of negative effects or interactions. Anti-histamines come in at number two after benzo anti-convulsants. Prochlotperazine has a higher reported positive outcome, but many respondents reported negative effects from its use.

Sample title

GABA anti-convulsant reports highly negative

Several medications had a higher proportion of respondents reporting negative than positive effects.

Sample title

Some correlation between efficacy and prescription rates

The most prescribed medication are not always the ones with the highest reported efficacy (by CEV)

The survey reveals that some commonly-prescribed medications have low rates of success.

Sample title
Sample title

Want to dig into the data yourself?

A range of medications are prescribed for VM, and these cover very different types of drugs. The survey revealed which of these enjoyed most popular success, and which ones were most prone to negative interactions.

Has this survey been useful to you?

The information presented here is the result of a survey, and shows aggregated data submitted by VM sufferers. This information does not constitute medical advice, and MalaDIO does not endorse any medications or other treatments. Any changes to your treatment should be taken under medical advice.